TNF-a is an critical modulator of MMP exercise, specifically gelatinaseB/MMP9 [32,33] which is critical for extracellular matrix remodelling and has also been proven to engage in a pivotal part in BM restoration pursuing myelosuppression [34]
TNF-a KO mice are resistant to irradiation-induced BM cell apoptosis. A. TUNEL assay on...