On the other hand, residues these kinds of as K22 and R41H42 that are critical for the Vif-mediated degradation of A3G are dispensable for Vif-mediated degradation of the two full-duration A3F and the carboxyl-terminal area of A3F
Mutant VifK22E and VifRH41/42AA ended up as effective as WT Vif (Fig. 4B) in...