Product Name :
Linerixibat
CAS No.:
1345982-69-5
Purity :
99.98%
Shipping:
Room temperature in the continental U.S. Other areas may vary.
Storage :
Powder: -20°C, 3 years; 4°C, 2 yearsIn solvent: -80°C, 2 years; -20°C, 1 year
SMILES:
O=C(O)CC(NCC1=C(OC)C=C(C2=C1)[C@@H](C3=CC=CC=C3)N[C@](CC)(CCCC)CS2(=O)=O)CC(O)=O
Product Description :
Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally active apical sodium-dependent bile acid transporter (ASBT) inhibitor with an IC50 of 42 nM human ASBT. Linerixibat can be used as lipid-lowering agent.{{1268524-70-4} site|{1268524-70-4} Technical Information|{1268524-70-4} In Vitro|{1268524-70-4} manufacturer} Linerixibat has the potential for type 2 diabetes and Primary Biliary Cholangitis treatment.
Formula:
C28H38N2O7S
Molecular Weight :
546.68
Synonyms:
GSK2330672
Additional Information:
|CAS No. 1345982-69-5 ; |Synonyms GSK2330672 ; |Formula C28H38N2O7S ; |Molecular Weight 546.68 ; |SMILES O=C(O)CC(NCC1=C(OC)C=C(C2=C1)[C@@H](C3=CC=CC=C3)N[C@](CC)(CCCC)CS2(=O)=O)CC(O)=O ; |Target Apical Sodium-Dependent Bile Acid Transporter ; |Product Description Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally active apical sodium-dependent bile acid transporter (ASBT) inhibitor with an IC50 of 42 nM human ASBT.{{2410796-79-9} medchemexpress|{2410796-79-9} Technical Information|{2410796-79-9} Data Sheet|{2410796-79-9} manufacturer} Linerixibat can be used as lipid-lowering agent.PMID:20301620 Linerixibat has the potential for type 2 diabetes and Primary Biliary Cholangitis treatment. ; |Format Solid ; |Color White to off-white ; |Purity 99.98% ; |Shipping Room temperature in the continental U.S. Other areas may vary. ; |Storage Powder: -20°C, 3 years; 4°C, 2 yearsIn solvent: -80°C, 2 years; -20°C, 1 year ; |Solubility Overview Soluble in DMSO