Product Name :
Benznidazol
Description:
Benznidazol (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.
CAS:
22994-85-0
Molecular Weight:
260.25
Formula:
C12H12N4O3
Chemical Name:
N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide
Smiles :
[O-][N+](=O)C1=NC=CN1CC(=O)NCC1C=CC=CC=1
InChiKey:
CULUWZNBISUWAS-UHFFFAOYSA-N
InChi :
InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Amsacrine} web|{Amsacrine} Cell Cycle/DNA Damage|{Amsacrine} Technical Information|{Amsacrine} Purity|{Amsacrine} manufacturer|{Amsacrine} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Benznidazol (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.{{β-Muricholic acid} medchemexpress|{β-Muricholic acid} Endogenous Metabolite|{β-Muricholic acid} Activator|{β-Muricholic acid} Protocol|{β-Muricholic acid} Formula|{β-Muricholic acid} manufacturer} 35 μM for Colombian T.PMID:24318587 cruzi strains, and has been used in the treatment of Chagas disease.|Product information|CAS Number: 22994-85-0|Molecular Weight: 260.25|Formula: C12H12N4O3|Chemical Name: N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide|Smiles: [O-][N+](=O)C1=NC=CN1CC(=O)NCC1C=CC=CC=1|InChiKey: CULUWZNBISUWAS-UHFFFAOYSA-N|InChi: InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (192.12 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Benznidazole (100 mg/kg/day, p.o., 30 days) produces a decrease in electrocardiographic alterations, fewer modifications in the affinity and density of cardiac-receptors, and few isolated areas of fibrosis in the heart, in mice infected with Trypanosoma cruzi Tulahuen strain or SGO-Z12 isolate and treated at 180 days post infection (p.i.) (i.e. chronic phase) with Benznidazole.|Products are for research use only. Not for human use.|
