Product Name :
CL264
Description:
CL264 is a TLR7-specific agonist for innate immune signals research.
CAS:
1510712-69-2
Molecular Weight:
413.43
Formula:
C19H23N7O4
Chemical Name:
2-[(4-{[6-amino-2-(butylamino)-8-oxo-8,9-dihydro-7H-purin-9-yl]methyl}phenyl)formamido]acetic acid
Smiles :
CCCCNC1=NC(N)=C2NC(=O)N(CC3C=CC(=CC=3)C(=O)NCC(O)=O)C2=N1
InChiKey:
BXJWQQWEBUICHY-UHFFFAOYSA-N
InChi :
InChI=1S/C19H23N7O4/c1-2-3-8-21-18-24-15(20)14-16(25-18)26(19(30)23-14)10-11-4-6-12(7-5-11)17(29)22-9-13(27)28/h4-7H,2-3,8-10H2,1H3,(H,22,29)(H,23,30)(H,27,28)(H3,20,21,24,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Probucol} MedChemExpress|{Probucol} Virus Protease|{Probucol} Protocol|{Probucol} Data Sheet|{Probucol} custom synthesis|{Probucol} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Tapinarof} MedChemExpress|{Tapinarof} Immunology/Inflammation|{Tapinarof} Biological Activity|{Tapinarof} Description|{Tapinarof} custom synthesis|{Tapinarof} Autophagy}
Additional information:
CL264 is a TLR7-specific agonist for innate immune signals research.|Product information|CAS Number: 1510712-69-2|Molecular Weight: 413.43|Formula: C19H23N7O4|Chemical Name: 2-[(4-{[6-amino-2-(butylamino)-8-oxo-8,9-dihydro-7H-purin-9-yl]methyl}phenyl)formamido]acetic acid|Smiles: CCCCNC1=NC(N)=C2NC(=O)N(CC3C=CC(=CC=3)C(=O)NCC(O)=O)C2=N1|InChiKey: BXJWQQWEBUICHY-UHFFFAOYSA-N|InChi: InChI=1S/C19H23N7O4/c1-2-3-8-21-18-24-15(20)14-16(25-18)26(19(30)23-14)10-11-4-6-12(7-5-11)17(29)22-9-13(27)28/h4-7H,2-3,8-10H2,1H3,(H,22,29)(H,23,30)(H,27,28)(H3,20,21,24,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 25 mg/mL (60.PMID:24013184 47 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Toll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7 is expressed predominantly in plasmacytoid dendritic cells (pDCs), macrophages and B cells. Many TLR7 modulators are interferon inducers, anti-cancer agents, anti-infectious agents, therapeutic agents for immunological diseases and vaccine adjuvants.|Products are for research use only. Not for human use.|
