They reported a reduction in hot flash severity scores of 31 to

They reported a reduction in hot flash severity scores of 31 to 61 versus 27 in placebo, as well as a reduction in hot flash frequency of 30 to 58 versus 19 in placebo. The effects of Scitalopram compared with placebo in treating hot flash in 205 females was studied by Freeman et al.45 They found that Scitalopram was more efficient in lowering hot flash severity just after eight weeks when compared with placebo. Stearns et al. Studied the effects of paroxetine within the treatment of hot flash.46 A 62.2 decrease was observed in hot flash with paroxetine using the dosage of 12.five mg in addition to a 64.4 decrease with all the dosage of 25 mg just after six weeks of remedy, and a 37.eight lower by placebo. The imply daily hot flash frequency using a dosage of 12.5 mg decreased from 7.Xanomeline 1 to 3.eight, with a dosage of 25 mg it decreased from 6.Dazodalibep 4 to 3.three, and in placebo from six.six to four.eight. A further study on the effects of venlafaxine on hot flash of women brought on by breast cancer was carried out by Carpenter et al.47 This study indicated that venlafaxine was additional successful than placebo. Gordon et al. also reported that sertraline was extra effective in reducing hot flashes in 102 girls with menopause compared to placebo.48The outcomes of those studies are comparable towards the present study which can be because of their related mechanism. Nonetheless, the results in the study by Grady et al. indicated that sertraline was not productive around the frequency and severity of perimenopausal and postmenopausal hot flashes.49 SuvantoLuukkonen et al. cond-ucted a randomized clinical trial for the duration of 9 months around the effects of citalopram and fluoxetine on hot flashes in 150 menopausal females. They reported that there was no substantial difference between the groups relating to hot flash frequency.50 Bouchard et al. studied the effects ofJournal of Caring Sciences, Jun 2013; two (2), 131-140|Copyright 2013 by Tabriz University of Medical SciencesBani et al.desvenlafaxine on vasomotor symptoms, in 35 regions of Europe, two regions of South Africa, and 1 region of Mexico.51 In week 12 no significant difference was observed inside the reduction of mean frequency of each day hot flashes between the groups. Within the present study folic acid had no unwanted side effects; for that reason, it might be applied for minimizing hot flashes and enhancing the women’s excellent of life.PMID:23935843 Considering the fact that you can find a limited quantity of research on the effect of folic acid on menopausal hot flash, additional studies on this matter are recommended.ConclusionThe final results with the present study indicated that folic acid and placebo have been each productive within the improvement of hot flash. On the other hand, folic acid was additional powerful. Folic acid is really a protected, reasonably priced, and acceptable medication for ladies; therefore, it may be considered as an option process for relieving menopausal hot flashes.Ethical issuesNone to be declared.Conflict of interestThe authors declare no conflict of interest within this study.AcknowledgmentsOur appreciation goes to the analysis deputy of Tabriz University of Health-related Sciences for the economic help, Dr. Yousef Javadzadeh, an academic member in the Division of Pharmacy, Tabriz University of Health-related Sciences, for making the placebo, the employees of Al-Zahra teaching hospital of Rasht, and all of the females participating in this study.
People infected with human immunodeficiency virus variety 1 (HIV-1) frequently suffer from neurocognitive impairments which are referred to as HIV-1-associated neurocognitive problems (HAND) [1,2]. The severity of HAND varies, ranging from asymptomatic ne.