product name Trospium chloride
Description: Trospium chloride is a competitive muscarinic cholinergic receptor antagonist. It antagonizes the effect of acetylcholine on muscarinic receptors in cholinergically innervated organs including the bladder. Its parasympatholytic action reduces the tonus of smooth muscle in the bladder. Receptor assays showed that trospium chloride has negligible affinity for nicotinic receptors as compared to muscarinic receptors at concentrations obtained from therapeutic doses.
References: Int J Clin Pract. 2010 Oct;64(11):1535-40; Ann Pharmacother. 2009 Feb;43(2):283-95.
427.96
Formula
C25H30NO3.Cl
CAS No.
10405-02-4
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 41 mg/mL (95.8 mM)
Water: 86 mg/mL (201 mM)
Ethanol: 42 mg/mL (98.1 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19390577
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Trospium chloride
Description: Trospium chloride is a competitive muscarinic cholinergic receptor antagonist. It antagonizes the effect of acetylcholine on muscarinic receptors in cholinergically innervated organs including the bladder. Its parasympatholytic action reduces the tonus of smooth muscle in the bladder. Receptor assays showed that trospium chloride has negligible affinity for nicotinic receptors as compared to muscarinic receptors at concentrations obtained from therapeutic doses.
References: Int J Clin Pract. 2010 Oct;64(11):1535-40; Ann Pharmacother. 2009 Feb;43(2):283-95.
427.96
Formula
C25H30NO3.Cl
CAS No.
10405-02-4
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 41 mg/mL (95.8 mM)
Water: 86 mg/mL (201 mM)
Ethanol: 42 mg/mL (98.1 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19390577
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |