product name Tioxolone
Description: Tioxolone is a potent metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 NM. Tioxolone is reported to possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics (e.g. hair shampoos and skin cleansers), due to claims for its oil-regulating and antibacterial properties. The three-dimensional framework of Tioxolone is further stabilized by π-π interactions between the oxathiolone and benzene rings in partially overlapping molecules.
References: Acta Crystallogr C. 2004 Jun;60(Pt 6):o395-6; Exp Mol Med. 2011 May 31;43(5):313-21.
168.17
Formula
C7H4O3S
CAS No.
4991-65-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 34 mg/mL (202.2 mM)
Water: < 1 mg/mL
Ethanol: 34 mg/mL (202.17 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19404580
| In Vitro |
In vitro activity: Tioxolone is reported to possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics (e.g. hair shampoos and skin cleansers), due to claims for its oil-regulating and antibacterial properties. The three-dimensional framework of Tioxolone is further stabilized by π-π interactions between the oxathiolone and benzene rings in partially overlapping molecules. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | Tioxolone, a Benzoxathiol derivatives, has been used in the local therapy of psoriasis vulgaris and acne, and also reported to have anti-bacterial, anti-mycotic, and cytostatic properties. |
| Animal model | |
| Formulation & Dosage | |
| References | Acta Crystallogr C. 2004 Jun;60(Pt 6):o395-6; Exp Mol Med. 2011 May 31;43(5):313-21. |
Related Posts
product name Tioxolone
Description: Tioxolone is a potent metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 NM. Tioxolone is reported to possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics (e.g. hair shampoos and skin cleansers), due to claims for its oil-regulating and antibacterial properties. The three-dimensional framework of Tioxolone is further stabilized by π-π interactions between the oxathiolone and benzene rings in partially overlapping molecules.
References: Acta Crystallogr C. 2004 Jun;60(Pt 6):o395-6; Exp Mol Med. 2011 May 31;43(5):313-21.
168.17
Formula
C7H4O3S
CAS No.
4991-65-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 34 mg/mL (202.2 mM)
Water: < 1 mg/mL
Ethanol: 34 mg/mL (202.17 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19404580
| In Vitro |
In vitro activity: Tioxolone is reported to possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics (e.g. hair shampoos and skin cleansers), due to claims for its oil-regulating and antibacterial properties. The three-dimensional framework of Tioxolone is further stabilized by π-π interactions between the oxathiolone and benzene rings in partially overlapping molecules. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | Tioxolone, a Benzoxathiol derivatives, has been used in the local therapy of psoriasis vulgaris and acne, and also reported to have anti-bacterial, anti-mycotic, and cytostatic properties. |
| Animal model | |
| Formulation & Dosage | |
| References | Acta Crystallogr C. 2004 Jun;60(Pt 6):o395-6; Exp Mol Med. 2011 May 31;43(5):313-21. |