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product name Tanshinone IIA


Description: Tanshinone IIA is derived from phenanthrene-quinone, which can be isolated from Salvia miltiorrhiza BUNGE. The compound can promote anti-inflammatory, anti-oxidative, and cytotoxic activity, and well as induce apoptosis. Tanshinone IIA has been shown to decrease levels of iNOS and inhibit synthesis of TNF-α, nitric oxide, and IL-1β. Research has indicated that Tanshinone IIA can inhibit the migration of human aortic smooth muscle cells (HASMC) and AP-1 DNA-binding.

References: Int J Mol Med. 2010 Feb;25(2):231-6; J Cell Biochem. 2008 May 1;104(1):15-26.



Molecular Weight (MW)

294.34 
Formula

C19H18O3 
CAS No.

568-72-9  
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: > 10 mM 
Water
Ethanol
Solubility (In vivo)

 
Synonyms

 

other peoduct :

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

OTS-966

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Author: Sodium channel