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product name Sulfacetamide Sodium


Description: Sulfacetamide Sodium is an anti-biotic. It is classified as sulfonamide antibiotic chemically. Sulfacetamide is able to inhibit the growth of all isolated strains. Depending on the type of bacteria concentrations of 0.006 up to 6.4% sodium sulfacetamide proved to be effective. Simultaneously, all patients.

References: Langmuir. 2016 Aug 9;32(31):7814-20.



Molecular Weight (MW)

236.22 
Formula

C8H10N2O3S.Na 
CAS No.

127-56-0 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 19 mg/mL (80.4 mM)
Water: 51 mg/mL (215.9 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19396835

In Vitro

In vitro activity:  Sulfacetamide is a sulfonamide antibiotic. Sulfacetamide is able to inhibit the growth of all isolated strains. Depending on the type of bacteria concentrations of 0.006 up to 6.4% sodium sulfacetamide proved to be effective. Simultaneously, all patients were treated with sulfacetamide containing ointment and/or eye drops 4 times daily for maximum of 14 days. With swabs taken at intervals of 7 and 14 days no bacterial growth was detected. Sulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis. Sulfacetamide has been investigated for use in the treatment of pityriasis versicolor and rosacea. It may also have anti-inflammatory properties when used to treat blepharitis or conjunctivitis. It is believed to work by limiting the presence of folic acid which bacteria need to survive. It has been suggested that sulfacetamide may also serve as a treatment for mild forms of hidradenitis suppurativa. Sulfacetamide has antibacterial activity and is used to control acne. Some research indicates that sulfacetamide derivatives may act as antifungals by an CYP51A1-independent mechanism 


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References Klin Monbl Augenheilkd. 1992 Mar;200(3):182-6; Met Based Drugs. 2000;7(1):49-54.  

PF-04418948

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Author: Sodium channel

Share this post on:

product name Sulfacetamide Sodium


Description: Sulfacetamide Sodium is an anti-biotic. It is classified as sulfonamide antibiotic chemically. Sulfacetamide is able to inhibit the growth of all isolated strains. Depending on the type of bacteria concentrations of 0.006 up to 6.4% sodium sulfacetamide proved to be effective. Simultaneously, all patients.

References: Langmuir. 2016 Aug 9;32(31):7814-20.



Molecular Weight (MW)

236.22 
Formula

C8H10N2O3S.Na 
CAS No.

127-56-0 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 19 mg/mL (80.4 mM)
Water: 51 mg/mL (215.9 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19396835

In Vitro

In vitro activity:  Sulfacetamide is a sulfonamide antibiotic. Sulfacetamide is able to inhibit the growth of all isolated strains. Depending on the type of bacteria concentrations of 0.006 up to 6.4% sodium sulfacetamide proved to be effective. Simultaneously, all patients were treated with sulfacetamide containing ointment and/or eye drops 4 times daily for maximum of 14 days. With swabs taken at intervals of 7 and 14 days no bacterial growth was detected. Sulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis. Sulfacetamide has been investigated for use in the treatment of pityriasis versicolor and rosacea. It may also have anti-inflammatory properties when used to treat blepharitis or conjunctivitis. It is believed to work by limiting the presence of folic acid which bacteria need to survive. It has been suggested that sulfacetamide may also serve as a treatment for mild forms of hidradenitis suppurativa. Sulfacetamide has antibacterial activity and is used to control acne. Some research indicates that sulfacetamide derivatives may act as antifungals by an CYP51A1-independent mechanism 


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References Klin Monbl Augenheilkd. 1992 Mar;200(3):182-6; Met Based Drugs. 2000;7(1):49-54.  

PF-04418948

Share this post on:

Author: Sodium channel