product name Sodium salicylate
References: Science. 1994 Aug 12;265(5174):956-9; Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2869-73.
161.11
Formula
C7H6O3.Na
CAS No.
54-21-7
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 32 mg/mL (198.6 mM)
Water: 32 mg/mL (198.6 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :
| In Vitro |
In vitro activity: Sodium salicylate acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. Sodium salicylate inhibits the activation of NF-kappa B, and also inhibits NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells. Sodium salicylate also induces apoptosis via p38 MAPK and inhibits TNF-induced JNK/stress-activated protein kinase activation. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Science. 1994 Aug 12;265(5174):956-9; Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2869-73. |
