product name Racecadotril
Description: Racecadotril, also known as acetorphan, is a peripherally acting enkephalinase inhibitor. It protects endogenous enkephalins from degradation and has an IC50 of 4.5 μM against enkephalinase. Unlike other opioid medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect, it reduces the secretion of water and electrolytes into the intestine.
References: Arch Dis Child. 2016 Mar;101(3):234-40.
385.48
Formula
C21H23NO4S
CAS No.
81110-73-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 22 mg/mL (57.1 mM)
Water: <1 mg/mL
Ethanol: 77 mg/mL (199.78mM)
Solubility (In vivo)
Synonyms
Acetorphan
other peoduct :
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