product name Quinacrine 2HCl
Description: Quinacrine 2HCl is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. Quinacrine dihydrochloride is a non-specific PLA2 (phospholipase A2) inhibitor. Quinacrine, Dihydrochloride acts as an AChR (acetylcholine receptor) antagonist. Quinacrine dihydrochloride suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 μM). This compound also inhibits MAO (monoamine oxidase). Quinacrine, Dihydrochloride is an inhibitor of cPLA2, MAO-A and MAO-B.
References: Biochem Biophys Res Commun. 1991 Dec 16;181(2):714-21.
472.88
Formula
C23H30ClN3O.2HCl
CAS No.
69-05-6
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 14 mg/mL (29.6 mM)
Water: 53 mg/mL (112.1 mM)
Ethanol: 28 mg/mL (59.2 mM)
Solubility (In vivo)
Synonyms
other peoduct :
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