product name Pyridostigmine Bromide
Description: Pyridostigmine Bromide is a parasympathomimetic and a reversible cholinesterase inhibitor. It is a cholinesterase inhibitor with a slightly longer duration of action than neostigmine. Pyridostigmine Bromide is primarily used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants. It binds reversibly to acetylcholinesterase active sites in the peripheral nervous system, thereby preventing the breakdown of acetylcholine. This leads to an accumulation of acetylcholine at cholinergic synapses and facilitates transmission of impulses across the neuromuscular junction.
References: Neuroscience. 2013 Aug 29;246:391-6; Luminescence. 2011 Nov-Dec;26(6):510-7.
261.12
Formula
C9H13BrN2O2
CAS No.
101-26-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 52 mg/mL (199.1 mM)
Water: 52 mg/mL (199.1 mM)
Ethanol:
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19390580
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Pyridostigmine Bromide
Description: Pyridostigmine Bromide is a parasympathomimetic and a reversible cholinesterase inhibitor. It is a cholinesterase inhibitor with a slightly longer duration of action than neostigmine. Pyridostigmine Bromide is primarily used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants. It binds reversibly to acetylcholinesterase active sites in the peripheral nervous system, thereby preventing the breakdown of acetylcholine. This leads to an accumulation of acetylcholine at cholinergic synapses and facilitates transmission of impulses across the neuromuscular junction.
References: Neuroscience. 2013 Aug 29;246:391-6; Luminescence. 2011 Nov-Dec;26(6):510-7.
261.12
Formula
C9H13BrN2O2
CAS No.
101-26-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 52 mg/mL (199.1 mM)
Water: 52 mg/mL (199.1 mM)
Ethanol:
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19390580
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |