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product name Propranolol HCl


Description: Propranolol HCl (also known as AY-64043, ICI-45520, NCS-91523) is a competitive and non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM. It blocks bothh β1 and β2 adrenergic receptors. Propranolol hydrochloride also has been shown to inhibit the formation of phospholipase D-derived diacylglycerol by inhibiting cytosolic phosphatidate phosphohydrolase; making propranolol a useful tool for investigating phospholipase C-/D-mediated DAG production. 

References: Mol Pharmacol. 1996 Jan;49(1):198-206.



Molecular Weight (MW)

295.8 
Formula

C16H21NO2.HCl 
CAS No.

318-98-9 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 59 mg/mL (199.5 mM) 
Water: 6 mg/mL (20.3 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

AY-64043, ICI-45520, NCS-91523 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19398885

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

RG7112

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Author: Sodium channel

Share this post on:

product name Propranolol HCl


Description: Propranolol HCl (also known as AY-64043, ICI-45520, NCS-91523) is a competitive and non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM. It blocks bothh β1 and β2 adrenergic receptors. Propranolol hydrochloride also has been shown to inhibit the formation of phospholipase D-derived diacylglycerol by inhibiting cytosolic phosphatidate phosphohydrolase; making propranolol a useful tool for investigating phospholipase C-/D-mediated DAG production. 

References: Mol Pharmacol. 1996 Jan;49(1):198-206.



Molecular Weight (MW)

295.8 
Formula

C16H21NO2.HCl 
CAS No.

318-98-9 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 59 mg/mL (199.5 mM) 
Water: 6 mg/mL (20.3 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

AY-64043, ICI-45520, NCS-91523 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19398885

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

RG7112

Share this post on:

Author: Sodium channel