product name Polymyxin B sulphate
Description: Polymyxin B (also known as Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections. Polymyxin B sulfate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
References: Am J Physiol. 1991 Jul;261(1 Pt 2):R26-31; Eur J Pharmacol. 1991 May 25;207(1):17-22.
1301.56
Formula
C56H98N16O13.H2SO4
CAS No.
1405-20-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: <1 mg/mL
Water: 100 mg/mL (76.83 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
Aerosporin, PMB, Poly-RX
other peoduct :
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
