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product name Norfloxacin


Description: Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase. Norfloxacin is a synthetic chemotherapeutic antibacterial agent occasionally used to treat common as well as complicated urinary tract infections. It is a first generation synthetic fluoroquinolone and is approved for the treatment of urinary tract infections, prostatitis, and sexually transmitted diseases, although it is no longer used for the latter due to bacterial resistance. 

References: Eur Urol. 1990;17 Suppl 1:13-8; Clin Infect Dis. 2007 Apr 1;44(7):977-80



Molecular Weight (MW)

319.33 
Formula

C16H18FN3O3 
CAS No.

70458-96-7 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 3 mg/mL (9.4 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

MK-0366 

other peoduct :

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

AMG-340

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Author: Sodium channel