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product name Nitrendipine


Description: Nitrendipine (also known as Bayotensin) is a dihydropyridine calcium channel blocker (CCB) with an IC50 of 95 NM. It is CCB with marked vasodilator action, it is classified as a dihydropyridine calcium channel blocker that is used in the treatment of primary hypertension to decrease blood pressure. It can also reduce the cardiotoxicity of cocaine. 

References: Proc Natl Acad Sci U S A. 1984 Oct;81(20):6388-92; Drugs. 2004;64(10):1135-48.



Molecular Weight (MW)

360.37
Formula

C18H20N2O6 
CAS No.

39562-70-4
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 72 mg/mL (199.8 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

Bayotensin

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19396408

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

Cot inhibitor-2

Share this post on:

Author: Sodium channel

Share this post on:

product name Nitrendipine


Description: Nitrendipine (also known as Bayotensin) is a dihydropyridine calcium channel blocker (CCB) with an IC50 of 95 NM. It is CCB with marked vasodilator action, it is classified as a dihydropyridine calcium channel blocker that is used in the treatment of primary hypertension to decrease blood pressure. It can also reduce the cardiotoxicity of cocaine. 

References: Proc Natl Acad Sci U S A. 1984 Oct;81(20):6388-92; Drugs. 2004;64(10):1135-48.



Molecular Weight (MW)

360.37
Formula

C18H20N2O6 
CAS No.

39562-70-4
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 72 mg/mL (199.8 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

Bayotensin

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19396408

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

Cot inhibitor-2

Share this post on:

Author: Sodium channel