product name Netilmicin Sulfate
Description: Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics. It is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin. Netilmicin Sulfate is a semisynthetic derivative of sisomicin. It shows activity against aminoglycoside-resistant bacteria and much decreased chronic toxicity in animals relative to sisomicin, gentamicin and tobramycin. Netilmicin Sulfate shows high activity against E. coli, Klebsiella, Enterobacter, Citrobacter, Proteus spp and Staph. Aureus. In addition, 87% of indole-positive Proteus strains, 90.7% of Serratia and 83.5% of Ps. Aeruginosa strains are sensitive to Netilmicin Sulfate.
References: Drugs. 1984 Jun;27(6):548-78.
1441.55
Formula
C21H41N5O7.2.5H2O4S
CAS No.
56391-57-2
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: <1 mg/mL
Water: 288 mg/mL (199.8 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :
| In Vitro |
In vitro activity: Netilmicin Sulfate is a semisynthetic derivative of sisomicin. It shows activity against aminoglycoside-resistant bacteria and much decreased chronic toxicity in animals relative to sisomicin, gentamicin and tobramycin. Netilmicin Sulfate shows high activity against E. coli, Klebsiella, Enterobacter, Citrobacter, Proteus spp and Staph. Aureus. In addition, 87% of indole-positive Proteus strains, 90.7% of Serratia and 83.5% of Ps. Aeruginosa strains are sensitive to Netilmicin Sulfate. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Drugs. 1984 Jun;27(6):548-78. |
