product name Nalidixic acid
Description: Nalidixic acid (also known as NSC-82174), a synthetic 1,8-naphthyridine antimicrobial agent, is the first of the synthetic quinolone antibiotics with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.Nalidixic acid is effective primarily against gram-negative bacteria, with minor anti-gram-positive activity. At lower concentrations, it acts in a bacteriostatic manner; At higher concentrations, it is bactericidal.
References: Int J Antimicrob Agents. 2012 Jul;40(1):9-17.
232.24
Formula
C12H12N2O3
CAS No.
389-08-2
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 6 mg/mL (25.8 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
NSC-82174
other peoduct :
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