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product name Hordenine


Description: Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties. It inhibits the uptake of norepinephrine in mammals, working as a stimulant. It is produced in nature by several varieties of plants in the family Cactaceae and by some in Acacia. Recent study shows that hordenine may be an effective inhibitor of hyperpigmentation. it inhibits melanogenesis by suppressing cAMP production, which is involved in the expression of melanogenesis-related proteins

References: J Pharm Pharmacol. 1989 Jun;41(6):421-3; Food Chem. 2013 Nov 1;141(1):174-81.



Molecular Weight (MW)

165.23 
Formula

C10H15NO 
CAS No.

539-15-1 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 33 mg/mL (199.7 mM) 
Water: <1 mg/mL
Ethanol: 33 mg/mL (199.7 mM) 
Solubility (In vivo)

 
Synonyms

 

other peoduct :

In Vitro

In vitro activity: Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties. It inhibits the uptake of norepinephrine in mammals, working as a stimulant. It is produced in nature by several varieties of plants in the family Cactaceae and by some in Acacia. Recent study shows that hordenine may be an effective inhibitor of hyperpigmentation. it inhibits melanogenesis by suppressing cAMP production, which is involved in the expression of melanogenesis-related proteins.


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References J Pharm Pharmacol. 1989 Jun;41(6):421-3; Food Chem. 2013 Nov 1;141(1):174-81. 

McMMAF

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Author: Sodium channel