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product name Ginkgolide A


Description: Ginkgolide A (also known as BN52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14.5 μM. Ginkgolides are biologically active terpenic lactones present in Ginkgo biloba. They are diterpenoids with 20-carbon skeletons, which are biosynthesized from geranylgeranyl pyrophosphate. It is extracted from the root bark and leaves of the Ginkgo biloba (ginkyo meaning “silver apricot”) tree found native in China. It is marketed to other countries that include Korea, France, the United States, etc. for the drug and clinical properties of the extracts. 

References: Chirality. 22 (2): 217–223; Medicinal Natural Products: A Biosynthetic Approach (3rd ed.). Wiley. pp. 230–232.



Molecular Weight (MW)

408.4
Formula

C20H24O9
CAS No.

15291-75-5
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 81 mg/mL (198.3 mM)
Water: <1 mg/mL
Ethanol: 2 mg/mL (4.9 mM)
Solubility (In vivo)

 
Synonyms

BN52020 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19422085

In Vitro

In vitro activity


Kinase Assay:  


Cell Assay:  

In Vivo  
Animal model  
Formulation & Dosage  
References  

LY2157300

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Author: Sodium channel