product name Gallamine Triethiodide
Description: Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM. Specifically, Gallamine Triethiodide is a mAChR M2 antagonist with pronounced cardioselectivity. It exerts its effects by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. It is a synthetic non-depolarizing blocking drug. The actions of gallamine triethiodide are similar to those of tubocurarine but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output.
References: J Pharmacol Exp Ther. 1986 Jan;236(1):219-23.
891.53
Formula
C30H60I3N3O3
CAS No.
65-29-2
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 100 mg/mL (112.2 mM)
Water: <1 mg/mL
Ethanol: 100 mg/mL (112.2 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19391041
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Gallamine Triethiodide
Description: Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM. Specifically, Gallamine Triethiodide is a mAChR M2 antagonist with pronounced cardioselectivity. It exerts its effects by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. It is a synthetic non-depolarizing blocking drug. The actions of gallamine triethiodide are similar to those of tubocurarine but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output.
References: J Pharmacol Exp Ther. 1986 Jan;236(1):219-23.
891.53
Formula
C30H60I3N3O3
CAS No.
65-29-2
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 100 mg/mL (112.2 mM)
Water: <1 mg/mL
Ethanol: 100 mg/mL (112.2 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19391041
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |