product name Fosinopril Sodium
Description: Fosinopril Sodium (also known as SQ28555) is the ester prodrug of fosinoprilat, an angiotensin-converting enzyme (ACE) inhibitor that is used for the treatment of hypertension and some types of chronic heart failure. Fosinopril Sodium is a phosphinic acid-containing ACE inhibitor that is effective in the treatment of hypertension. Fosinopril binds to the active site of ACE via targeting the zinc ions with its phosphinic acid moiety.
References: Am J Health Syst Pharm. 2000 Oct 1;57 Suppl 1:S3-7; Clin Pharmacokinet. 1997 Jun;32(6):460-80.
585.64
Formula
C30H45NO7P.Na
CAS No.
88889-14-9
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: <1 mg/mL
Water: 117 mg/mL (199.8 mM)
Ethanol: 4 mg/mL (6.8 mM)
Solubility (In vivo)
Synonyms
SQ28555
other peoduct :
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