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product name Flopropione


Description: Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist. Flopropione at temperatures below its T(g) shows no Lorentzian relaxation. Flopropione at temperatures below its T(g) has higher molecular mobility than Nifedipine. Flopropione shows Arrhenius temperature dependence throughout the entire temperature range and extrapolation of tau (beta) measured above T (g) by dielectric relaxation agreed with tau (beta) measured below T (g) by TAM/MDSC.

References: J Pharm Sci. 2000 Mar;89(3):408-16; Pharm Res. 2006 Oct;23(10):2277-90. 



Molecular Weight (MW)

182.17 
Formula

C9H10O4 
CAS No.

2295-58-1 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 36 mg/mL (197.61 mM) 
Water: <1 mg/mL
Ethanol: 36 mg/mL (197.61 mM) 
Solubility (In vivo)

 
Synonyms

 

other peoduct :

In Vitro

In vitro activity: Flopropione at temperatures below its T(g) shows no Lorentzian relaxation. Flopropione at temperatures below its T(g) has higher molecular mobility than Nifedipine. Flopropione shows Arrhenius temperature dependence throughout the entire temperature range and extrapolation of tau (beta) measured above T (g) by dielectric relaxation agreed with tau (beta) measured below T (g) by TAM/MDSC.


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References J Pharm Sci. 2000 Mar;89(3):408-16; Pharm Res. 2006 Oct;23(10):2277-90.  

BI 2538

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Author: Sodium channel