product name Esomeprazole sodium
Description: Esomeprazole Sodium, known as Nexium and H-199, is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg. Esomeprazole Sodium is the S-isomer of omeprazole and acts as a proton pump inhibitor gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.
References: Eur J Clin Pharmacol. 2008 Oct;64(10):935-51.
367.4
Formula
C17H18N3O3S.Na
CAS No.
161796-78-7
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 73 mg/mL (198.7 mM)
Water: 73 mg/mL (198.7 mM)
Ethanol: 73 mg/mL (198.7 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19399780
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
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In Vivo | |
Animal model | |
Formulation & Dosage | |
References |
Author: Sodium channel
product name Esomeprazole sodium
Description: Esomeprazole Sodium, known as Nexium and H-199, is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg. Esomeprazole Sodium is the S-isomer of omeprazole and acts as a proton pump inhibitor gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.
References: Eur J Clin Pharmacol. 2008 Oct;64(10):935-51.
367.4
Formula
C17H18N3O3S.Na
CAS No.
161796-78-7
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 73 mg/mL (198.7 mM)
Water: 73 mg/mL (198.7 mM)
Ethanol: 73 mg/mL (198.7 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19399780
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References |