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product name Dyphylline


Description: Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects. Dyphylline is a phosphodiesterase inhibitor used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It also acts as an adenosine receptor antagonist. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles

References: Ann Pharmacother. 1993 Jun;27(6):792-3.



Molecular Weight (MW)

254.24
Formula

C10H14N4O4
CAS No.

479-18-5
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 51 mg/mL (200.6 mM)
Water: <1 mg/mL
Ethanol: 51 mg/mL (200.6 mM)
Solubility (In vivo)

 
Synonyms

Diprophylline 

other peoduct :

In Vitro

In vitro activity:


Kinase Assay:


Cell Assay:

In Vivo  
Animal model  
Formulation & Dosage  
References  

MK-0775

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Author: Sodium channel