product name Cytisine
Description: Cytisine, also known as baptitoxine and sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. It has been used medically to help with smoking cessation. Cytisine is a nicotinic acetylcholine receptor agonist. It isa potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492 nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respectively).
References: N Engl J Med. 2014 Dec 18;371(25):2353-62; Br J Pharmacol. 2012 Feb;165(4):1006-16; N Engl J Med. 2011 Sep 29;365(13):1193-200.
190.24
Formula
C11H14N2O
CAS No.
485-35-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 38 mg/mL (199.7 mM)
Water: 38 mg/mL (199.7 mM)
Ethanol: 38 mg/mL (199.7 mM)
Solubility (In vivo)
Synonyms
Baphitoxine,Sophorine
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19390533
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Cytisine
Description: Cytisine, also known as baptitoxine and sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. It has been used medically to help with smoking cessation. Cytisine is a nicotinic acetylcholine receptor agonist. It isa potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492 nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respectively).
References: N Engl J Med. 2014 Dec 18;371(25):2353-62; Br J Pharmacol. 2012 Feb;165(4):1006-16; N Engl J Med. 2011 Sep 29;365(13):1193-200.
190.24
Formula
C11H14N2O
CAS No.
485-35-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 38 mg/mL (199.7 mM)
Water: 38 mg/mL (199.7 mM)
Ethanol: 38 mg/mL (199.7 mM)
Solubility (In vivo)
Synonyms
Baphitoxine,Sophorine
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19390533
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |