product name Clonidine HCl
Description: Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg. It is a sympathomimetic drug used for the treatment of high blood pressure, attention deficit hyperactivity disorder (ADHD), anxiety disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions. Clonidine treats high blood pressure by stimulating α2-receptors in the brain, which decreases peripheral vascular resistance, lowering blood pressure.
References: Clin Pharmacol Ther. 1980 Aug;28(2):167-76; Am J Physiol. 1997 Nov;273(5 Pt 2):R1569-71.
266.5
Formula
C9H9Cl2N3.HCl
CAS No.
4205-91-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 53 mg/mL (198.9 mM)
Water:
Ethanol: 53 mg/mL (198.9 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19395637
| In Vitro |
In vitro activity: Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Clonidine HCl
Description: Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg. It is a sympathomimetic drug used for the treatment of high blood pressure, attention deficit hyperactivity disorder (ADHD), anxiety disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions. Clonidine treats high blood pressure by stimulating α2-receptors in the brain, which decreases peripheral vascular resistance, lowering blood pressure.
References: Clin Pharmacol Ther. 1980 Aug;28(2):167-76; Am J Physiol. 1997 Nov;273(5 Pt 2):R1569-71.
266.5
Formula
C9H9Cl2N3.HCl
CAS No.
4205-91-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 53 mg/mL (198.9 mM)
Water:
Ethanol: 53 mg/mL (198.9 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19395637
| In Vitro |
In vitro activity: Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |