product name Ciprofloxacin
Description: Ciprofloxacin is a fluoroquinolone antibiotic, shows MIC90 (minimal inhibitory concentrations for 90%) of between 0.008 and 2 μg/ml for Enterobacteriaceae, Pseudomonas aeruginosa, Haemophilus influenzae, Neisseria gonorrhoeae, streptococci, Staphylococcus aureus, and Bacteroidesfragilis strains. Ciprofloxacin inhibits topoisomerase IV as a primary topoisomerase target and gyrase as a secondary target.
References: Antimicrob Agents Chemother. 1983 Apr;23(4):559-64; Antimicrob Agents Chemother. 1996 Oct;40(10):2321-6.
331.34
Formula
C17H18FN3O3
CAS No.
85721-33-1
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: <1 mg/mL
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
Bay o 9867
other peoduct :
| In Vitro |
In vitro activity: Ciprofloxacin is a fluoroquinolone antibiotic, shows MIC90 (minimal inhibitory concentrations for 90%) of between 0.008 and 2 μg/ml for Enterobacteriaceae, Pseudomonas aeruginosa, Haemophilus influenzae, Neisseria gonorrhoeae, streptococci, Staphylococcus aureus, and Bacteroidesfragilis strains. Ciprofloxacin inhibits topoisomerase IV as a primary topoisomerase target and gyrase as a secondary target. Ciprofloxacin shows an AUC (area under the curve) of 24 μg×h/ml. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Antimicrob Agents Chemother. 1983 Apr;23(4):559-64; Antimicrob Agents Chemother. 1996 Oct;40(10):2321-6. |
