product name Chloroprocaine HCl
Description: Chloroprocaine HCl is a a synthetic, local anesthetic used during surgical procedures. At the injection site, chloroprocaine hydrochloride acts by inhibiting sodium influx through binding to specific membrane sodium ion channels in the neuronal cell membranes, restricting sodium permeability, and blocking nerve impulse conduction. This leads to a loss of sensation. Chloroprocaine hydrochloride is short-acting due to rapid hydrolysis by pseudocholinesterase into para-aminobenzoic acid in plasma.
References: Anaesthesia. 1979 Oct;34(9):839-43; J Oral Ther Pharmacol. 1965 May;1:637-40.
307.22
Formula
C13H20Cl2N2O2
CAS No.
3858-89-7
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 61 mg/mL (198.6 mM)
Water: 61 mg/mL (198.6 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References |