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product name Chloroprocaine HCl


Description: Chloroprocaine HCl is a a synthetic, local anesthetic used during surgical procedures. At the injection site, chloroprocaine hydrochloride acts by inhibiting sodium influx through binding to specific membrane sodium ion channels in the neuronal cell membranes, restricting sodium permeability, and blocking nerve impulse conduction. This leads to a loss of sensation. Chloroprocaine hydrochloride is short-acting due to rapid hydrolysis by pseudocholinesterase into para-aminobenzoic acid in plasma. 

References: Anaesthesia. 1979 Oct;34(9):839-43; J Oral Ther Pharmacol. 1965 May;1:637-40.



Molecular Weight (MW)

307.22 
Formula

C13H20Cl2N2O2 
CAS No.

3858-89-7 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 61 mg/mL (198.6 mM) 
Water: 61 mg/mL (198.6 mM) 
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

 

other peoduct :

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

Acalabrutinib

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Author: Sodium channel