product name Bisoprolol fumarate
Description: Bisoprolol fumarate (also known as EMD33512) is a selective type β1 adrenergic receptor blocker. It is effective in the management of hypertension and angina pectoris. Bisoprolol hemifumarate has antihypertensive and potential cardioprotective activities. Devoid of intrinsic sympathomimetic activity, bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, decreasing cardiac contractility and rate, reducing cardiac output, and lowering blood pressure.
References: Am J Cardiol. 2015 Nov 15;116(10):1502-8; Fundam Clin Pharmacol. 1998;12(4):451-6.
441.52
Formula
C22H35NO8
CAS No.
104344-23-2
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 88 mg/mL (199.3 mM)
Water: 88 mg/mL (199.3 mM)
Ethanol: 88 mg/mL (199.3 mM)
Solubility (In vivo)
Synonyms
EMD33512
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19398546
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Bisoprolol fumarate
Description: Bisoprolol fumarate (also known as EMD33512) is a selective type β1 adrenergic receptor blocker. It is effective in the management of hypertension and angina pectoris. Bisoprolol hemifumarate has antihypertensive and potential cardioprotective activities. Devoid of intrinsic sympathomimetic activity, bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, decreasing cardiac contractility and rate, reducing cardiac output, and lowering blood pressure.
References: Am J Cardiol. 2015 Nov 15;116(10):1502-8; Fundam Clin Pharmacol. 1998;12(4):451-6.
441.52
Formula
C22H35NO8
CAS No.
104344-23-2
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 88 mg/mL (199.3 mM)
Water: 88 mg/mL (199.3 mM)
Ethanol: 88 mg/mL (199.3 mM)
Solubility (In vivo)
Synonyms
EMD33512
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19398546
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |