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product name Baicalein


Description: Baicalein, a flavone which is a type of flavonoid. is a CYP2C9 and prolyl endopeptidase inhibitor. Baicalin is found in several species in the genus Scutellaria, including Scutellaria lateriflora (blue skullcap). There are 10 mg/g baicalin in Scutellaria galericulata (common skullcap) leaves. Baicalin is the glucuronide of baicalein. It is a component of Chinese medicinal herb Huang-chin (Scutellaria baicalensis) and one of the chemical ingredients of Sho-Saiko-To, an herbal supplement. Baicalin is a known prolyl endopeptidase inhibitor, induces apoptosis in pancreatic cancer cells, and affects the GABA receptors. 

References: Drug Metab Dispos. 2009 Mar;37(3):629-34.



Molecular Weight (MW)

270.24
Formula

C15H10O5
CAS No.

491-67-8
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 54 mg/mL (199.8 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19422023

In Vitro

In vitro activity:


Kinase Assay:


Cell Assay:

In Vivo  
Animal model  
Formulation & Dosage  
References  

AZD4548

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Author: Sodium channel