product name Altretamine
Description: Altretamine (also known as Hexamethylmelamine, NSC13875, ENT50852) is an antineoplastic agent which also acts as a chemosterilant for male houseflies and other insects. Altretamine was approved by the U.S. FDA in 1990. It is indicated for use as a single agent in the palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with cisplatin and/or alkylating agent-based combination. The precise mechanism by which altretamine exerts its anti-cancer effect is unknown but it is classified by MeSH as an alkylating antineoplastic agent.
References: Clin Pharmacokinet. 1995 Jun;28(6):439-48.
210.28
Formula
C9H18N6
CAS No.
645-05-6
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 15 mg/mL (71.3 mM)
Water: <1 mg/mL
Ethanol: 33 mg/mL (156.9 mM)
Solubility (In vivo)
Synonyms
Hexamethylmelamine, NSC13875, ENT50852
other peoduct :
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Tenofovir (Disoproxil Fumarate)
