product name Adenine HCl
Description: Adenine hydrochloride is an adenine receptor agonist (Ki=18 nM at rat adenine receptor). In CHO cells transfected with adenine receptor it inhibits forskolin-stimulated cAMP formation. Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry. Adenine is used as an active component of boron-deficient media to grow yeast in order to assess whether yeast growth is stimulated by boron. It is useful as a local antiseptic and vitamin B4. Further, it is used in the microbial determination of niacin. It is also employed as a food supplement for adult rats to investigate the effects of dietary adenine overload.
References: Cell. 2015 May 7;161(4):710-3; Bioessays. 2016 Jan;38(1):27-40.
171.59
Formula
C5H5N5.HCl
CAS No.
2922-28-3
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 8 mg/mL (46.6 mM)
Water: 4 mg/mL (23.3 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19412534
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In vitro activity: Kinase Assay: Cell Assay: |
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