product name Abacavir sulfate
Description: Abacavir (also known as ABC, or 1592U89) is a commonly used nucleoside analogue with potent antiviral activity against HIV-1. Abacavir is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse transcriptase inhibitor (NRTI) type. Viral strains that are resistant to zidovudine (AZT) or lamivudine (3TC) are generally, but not always, sensitive to abacavir. It is on the World Health Organizations List of Essential Medicines, a list of the most important medication needed in a basic health system.
References: Lancet. 2002 Mar 2;359(9308):727-32; N Engl J Med. 2008 Feb 7;358(6):568-79.
335.35
Formula
C14H18N6O.1/2 H2O4S
CAS No.
188062-50-2
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: <1 mg/mL
Water: 36 mg/mL (107.4 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
1592U89
other peoduct :
| In Vitro |
In vitro activity: Abacavir is an analog of guanosine (a purine). Its target is the viral reverse transcriptase enzyme. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Lancet. 2002 Mar 2;359(9308):727-32; N Engl J Med. 2008 Feb 7;358(6):568-79. |
