product name Primidone
Description: Primidone (also known as NCI-C56360) is an anticonvulsant of the barbiturate class. It is a structural analog of phenobarbital and related to barbiturate-derivative anticonvulsants. The active metabolites, phenobarbital, p-hydroxyphenobarbital, and phenylethylmalonamide, are also anticonvulsants. Primidone was once a mainstay anticonvulsant in the treatment of partial and generalized seizures and was the treatment of choice for secondarily generalized seizures originating in the temporal lobes, especially when combined with phenytoin.
References: Clin Neuropharmacol. 2016 Jan-Feb;39(1):24-8; Wikipedia.
218.25
Formula
C12H14N2O2
CAS No.
125-33-7
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 44 mg/mL (201.6 mM)
Water: <1 mg/mL
Ethanol: 3 mg/mL (13.7 mM)
Solubility (In vivo)
Synonyms
NCI-C56360
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