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product name Phenytoin


Description: Phenytoin (also known as Diphenylhydantoin) is an inactive voltage-gated sodium channel stabilizer. It also is a potent multi-channel blockers, blocking K+ and Ca 2+ channels. It selectively blocks persistent INaP over shorter INaP actions and blocks high frequency repetitive firing of action potentials. Phenytoin Sodium is an anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant.    

References: Epilepsy Res. 2015 Aug;114:52-8; Rev Neurol (Paris). 2015 Feb;171(2):181-8.



Molecular Weight (MW)

274.25
Formula

C15H11N2NaO2
CAS No.

630-93-3
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 32 mg/mL (116.7 mM)
Water: 3 mg/mL (10.9 mM) 
Ethanol: 11 mg/mL (40.1 mM)
Solubility (In vivo)

 
Synonyms

Diphenylhydantoin Sodium

other peoduct :

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

BMS 777610

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Author: Sodium channel