product name Aminophylline
Description: Aminophylline, also known as Phyllocontin, is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist. Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. Its most common use is in the treatment of airway obstruction from asthma or COPD. It is used off-label as a reversal agent during nuclear stress testing.
References: Acad Emerg Med. 2003 Mar;10(3):192-7.
420.43
Formula
C16H24N10O4
CAS No.
317-34-0
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 53 mg/mL (126.1 mM)
Water: 84 mg/mL (199.8 mM)
Ethanol: <1 mg/L
Solubility (In vivo)
Synonyms
Phyllocontin
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