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product name Besifloxacin HCl


Description: Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic. Besifloxacin is a novel 8-chloro-fluoroquinolone agent with potent, bactericidal activity against prevalent and drug-resistant pathogens.besifloxacin is the most potent agent tested against gram-positive pathogens and anaerobes and is generally equivalent to comparator fluoroquinolones in activity against most gram-negative pathogens. Besifloxacin demonstrates potent, broad-spectrum activity, which is particularly notable against gram-positive and gram-negative isolates that are resistant to other fluoroquinolones and classes of antibacterial agents.

References: Ophthalmology. 2009 Sep;116(9):1615-1623.e1.; Antimicrob Agents Chemother. 2009 Aug;53(8):3552-60.



Molecular Weight (MW)

430.3 
Formula

C19H21ClFN3O3.HCl 
CAS No.

405165-61-9 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: <1 mg/mL 
Water: <1 mg/mL
Ethanol: <1 mg/mL 
Solubility (In vivo)

 
Synonyms

 

other peoduct :

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

Daun04

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Author: Sodium channel