product name Inulin
Description: Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan. Inulin causes (20 g/d and 40 g/d) a significant increase in bifidobacterial counts in feces. Inulin exerts a preferential stimulatory effect on numbers of the health-promoting genus Bifidobacterium, whilst maintaining populations of potential pathogens (Escherichia coli, Clostridium) at relatively low levels. Inulin combined with Bifidobacterium results in more potent inhibition of aberrant crypt foci (ACF) than administration of the two separately, achieving 80% inhibition of small ACF.
References: J Nutr. 1998 Jan;128(1):11-9; J Appl Bacteriol. 1993 Oct;75(4):373-80; Carcinogenesis. 1998 Feb;19(2):281-5.
Formula
C6nH10n+2O5n+1
CAS No.
9005-80-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 10 mg/mL
Water: 104 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :
| In Vitro |
In vitro activity: Inulin causes (20 g/d and 40 g/d) a significant increase in bifidobacterial counts in feces. Inulin exerts a preferential stimulatory effect on numbers of the health-promoting genus Bifidobacterium, whilst maintaining populations of potential pathogens (Escherichia coli, Clostridium) at relatively low levels. Inulin combined with Bifidobacterium results in more potent inhibition of aberrant crypt foci (ACF) than administration of the two separately, achieving 80% inhibition of small ACF. Inulin is made by a set of linear chains of fructose molecules, with a degree of polymerization (DP) ranging between 3 and 65, it can be fractionated into a slowly fermentable long-chain fraction (DP ranging from 10 to 65, average 25) or in a rapidly fermentable fraction made of oligofructose (DP ranging from 3 to 8, average 4). Long-chain inulin combined with short-chain oligofructose results in larger numbers of caecal, colonic and faecal bacteria of the Clostridium coccoides-Eubacterium rectale cluster than Control in rats, whereas OF alone does not affect this bacterial group in caecum, colon or faeces. Kinase Assay: Cell Assay: |
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| In Vivo | Inulin results in an increase in caecal wt and beta-glucosidase activity and a decrease in caecal pH were observed in rats given inulin-containing diets (with or without B. longum). |
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| Formulation & Dosage | |
| References | J Nutr. 1998 Jan;128(1):11-9; J Appl Bacteriol. 1993 Oct;75(4):373-80; Carcinogenesis. 1998 Feb;19(2):281-5. |
