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product name Hesperidin


Description: Hesperidin (HP) is a bioflavonoid that plays a role in plant defense and is abundant in citrus species, such as grapefruit, lemon and orange. Hesperidin is used effectively as a supplemental agent in complementary therapy protocols, since it possesses biological and pharmacological properties as an effective antioxidant, anti-inflammatory, anti-carcinogenic, and anti-hypertensive agent with lipid-lowering activity.

References: BMC Cancer. 2015 Oct 12;15:682; Arch Med Sci. 2016 Jun 1;12(3):486-93.



Molecular Weight (MW)

610.56 
Formula

C28H34O15 
CAS No.

520-26-3 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 122 mg/mL (199.81 mM) 
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

Cirantin 

other peoduct :

In Vitro

In vitro activity: hesperidin and linarin are two of the main constituent of Valerianas extract exhibiting a high affinity to KATP channel, which are related to the control of Ca++ concentration and release of GABA in synaptic nerve terminal, mainly on cells of SN.


Kinase Assay:


Cell Assay

In Vivo Hesperidin was dissolved in 1% carboxymethyl cellulose (CMC) and administered orally at a dose of 50 mg/kg for 10 consecutive days. In the control group, rats were treated with the corn oil and 1% CMC vehicle.
Animal model  
Formulation & Dosage  
References BMC Cancer. 2015 Oct 12;15:682; Arch Med Sci. 2016 Jun 1;12(3):486-93. 

Maytansinol

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Author: Sodium channel