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product name Sinomenine


Description: Sinomenine or cocculine is an alkaloid found in the root of the climbing plant Sinomenium acutum which is native to Japan and China. It is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis. However, its analgesic action against other kinds of pain is limited. Sinomenine is a morphinan derivative, related to opioids such as levorphanol and the non-opioid cough suppressant dextromethorphan. 

References: Biol Pharm Bull. 2005 Jan;28(1):105-9; Acta Med Okayama. 1976 Feb;30(1):1-20.



Molecular Weight (MW)

329.39
Formula

C19H23NO4 
CAS No.

115-53-7  
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: > 10 mM                   
Water
Ethanol
Solubility (In vivo)

 
Synonyms

 

other peoduct :

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

Entrectinib

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Author: Sodium channel