product name Oxiracetam
Description: Oxiracetam (also known as ISF 2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is used as a nootropic drug to improve memory and learning. Oxiracetam (50 mg/kg i.p.) improves avoidance acquisition in BALB/c mice. Oxiracetam (100 mg/kg i.p.) reduces the scopolamine-induced amnesic effect and decrease in acetylcholine level in the cortex and hippocampus. Oxiracetam pretreatment (30 mg/kg) prevents social recognition deficits produced with trimethyltin in rats.
References: Arch Int Pharmacodyn Ther. 1985 May;275(1):86-92; Pharmacol Biochem Behav. 1987 Jul;27(3):491-5.
158.16
Formula
C6H10N2O3
CAS No.
62613-82-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 31 mg/mL (196.0 mM)
Water: 31 mg/mL (196.0 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
ISF 2522
other peoduct :
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | Oxiracetam (50 mg/kg i.p.) improves avoidance acquisition in BALB/c mice. Oxiracetam (100 mg/kg i.p.) reduces the scopolamine-induced amnesic effect and decrease in acetylcholine level in the cortex and hippocampus. Oxiracetam pretreatment (30 mg/kg) prevents social recognition deficits produced with trimethyltin in rats. |
| Animal model | |
| Formulation & Dosage | |
| References | Arch Int Pharmacodyn Ther. 1985 May;275(1):86-92; Pharmacol Biochem Behav. 1987 Jul;27(3):491-5. |
