product name Paeonol
Description: Paeonol (also known as Peonol), a phenolic compound isolated from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, it inhibits MAO with an IC50 of about 50 μM. Paeonols pharmacologic functions include antiaggregatory,anti-inflammatory and anti-ischemia reperfusion damage and anti-lipid peroxidation effects
References: J Ethnopharmacol. 2004 Apr;91(2-3):351-5; Int Immunopharmacol. 2004 Feb;4(2):279-87.
166.17
Formula
C9H10O3
CAS No.
552-41-0
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 33 mg/mL (198.6 mM)
Water: <1 mg/mL
Ethanol: 33 mg/mL (198.6 mM)
Solubility (In vivo)
Synonyms
Peonol
other peoduct :
| In Vitro |
In vitro activity: Paeonol (Peonol) is a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum. It has demonstrated significant MAOI activity. MAO-A and MAO-B inhibiting effects with IC50 values of 54.6 μM and 42.5 μM respectively. Paeonol shows antimutagenic, anti-inflammatory and analgesic effects. Paeonol also inhibits anaphylactic reaction by regulating histamine and TNF-α. Kinase Assay: Cell Assay: |
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| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | J Ethnopharmacol. 2004 Apr;91(2-3):351-5; Int Immunopharmacol. 2004 Feb;4(2):279-87. |
