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product name Naratriptan


Description: Naratriptan is a triptan agent that is mainly used for the treatment of migraine headaches. Naratriptan is marketed by GlaxoSmithKline and is available in 2.5 mg tablets. The mechanism of action for Naratriptan is to act as a selective 5-HT1 receptor subtype agonist. Naratriptan is used for the treatment of the acute migraine attacks and the symptoms of migraine, including severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound or light.

References: J Headache Pain. 2011 Aug;12(4):399-403.



Molecular Weight (MW)

371.93 
Formula

C17H25N3O2S.HCl 
CAS No.

143388-64-1 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 74 mg/mL (199.0 mM)
Water: 22 mg/mL (59.2 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

 

other peoduct :

In Vitro

In vitro activity: Naratriptan is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of migraine headaches. Naratriptan is available in 2.5 mg tablets. It is a selective 5-HT1 receptor subtype agonist. Naratriptan is used for the treatment of the acute migraine attacks and the symptoms of migraine, including severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound or light.


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References Cephalalgia. 1997 May;17(3):145-52.

alpha-Amanitin

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Author: Sodium channel