product name Ethisterone
Description: Ethisterone is a progestogen hormone that is being considered to treat prostate cancer. It is the first orally active progestin, ethisterone (pregneninolone, 17α-ethynyltestosterone or 19-norandrostane), the 17α-ethynyl analog of testosterone. Ethisterone is a progestogen that counteracts estrogenic proliferative effects on the endometrium. Ethisterone (dose range: 40 μg-5 mg/day × 6) stimulates weight gain but has a rather weak effect on the sulphate pools and incorporation rates in mice.
References: Acta Pharmacol Toxicol (Copenh). 1971;29(23):177-93.
312.45
Formula
C21H28O2
CAS No.
434-03-7
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: <1 mg/mL
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19418096
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | Ethisterone (dose range: 40 μg-5 mg/day × 6) stimulates weight gain but has a rather weak effect on the sulphate pools and incorporation rates in mice. Ethisterone results in rapid increases in labeling indexes and scleroblast population began simultaneously in the central portion in the posterior margin of the joint plate in adult females of the medaka, Oryzias latipes, and the population becomes approximately ten times that in the control fish on the fifth day. |
| Animal model | |
| Formulation & Dosage | |
| References | Acta Pharmacol Toxicol (Copenh). 1971;29(23):177-93. |
