product name Chlorambucil
Description: Chlorambucil is a nitrogen mustard alkylating agent, it is an orally-active antineoplastic aromatic nitrogen mustard that is primarily used in the treatment of chronic lymphocytic leukemia. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.
References: Arch Biochem Biophys. 2015 Jan 15;566:7-14.
304.21
Formula
C14H19Cl2NO2
CAS No.
305-03-3
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 60 mg/mL (197.2 mM)
Water: <1 mg/mL
Ethanol: 60 mg/mL (197.2 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19411960
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In vitro activity: Kinase Assay: Cell Assay: |
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