product name Procainamide HCl
Description: Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias. Procainamide hydrochloride is the hydrochloride salt preparation of Procainamide, a potent blocker of Na+ channels. Procainamide demonstrates antiarrhythmic effects correlated with blockade of the Na+ channels. Procainamide hydrochloride is an inhibitor of DNA methyltransferase.
References: JPharmacol Rep. 2016 Jun;68(3):654-61.
271.79
Formula
C13H22ClN3O
CAS No.
614-39-1
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 54 mg/mL (198.6 mM)
Water:
Ethanol: 54 mg/mL (198.6 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/1941100
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References |