Share this post on:

product name Z-VAD-FMK (Caspase Inhibitor VI)


Description: Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies. Z-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes.

References: Garcia-Calvo M, et al. J Biol Chem. 1998, 273(49), 32608-32613.



Molecular Weight (MW)

453.46
Formula

C21H28FN3O7
CAS No.

161401-82-7
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 90 mg/mL (198.47 mM)
Water: <1 mg/mL (slightly soluble or insoluble)
Ethanol:
Solubility (In vivo)

 
Chemical Name

 L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-

other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19404998

Z-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes. As an irreversible general caspase inhibitor, it is useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I, this inhibitor does not require pretreatment with esterase for in vitro studies. A 10 mM (1 mg/221 µl) solution of Caspase Inhibitor VI in DMSO is also available.
In Vivo  
Animal model  
Formulation & Dosage  
Reference Garcia-Calvo M, et al. J Biol Chem. 1998, 273(49), 32608-32613.

Regorafenib